Endocrine Abstracts

Backgraound: The liver occupies a central position in lipid metabolism. Free fatty acids (FFAs) are taken up by the liver to join the hepatic pool of FFA, a portion of which the liver synthesizes. Fatty liver occurs when lipid accumulation exceeds the normal 5% of liver weight. In the macrovesicular type, large fat droplets balloon the liver cell, displacing the nucleus to the periphery of the cell, like an adipocyte. Triglyceride accumulates most commonly because it has the h...

Backgraound: Fatty liver can relate with arteriosclerosis. We investigated the atherogenic index in the patients with fatty liver.Methods: Ninety-one patients with hyperlipidemia and 47 healthy subjects were included in the study. Fasting plasma levels of lipids were detected. Liver echogenity was measured by 3.75 mHz ultrasound probe and was graded by comparison with renal paranchymal echogenity. Atherogenic index was calculated as the ratio of plasma l...

Background: Primary hyperparathyroidism (pHPT) is an important endocrinologic cause of metabolic bone disorder in human. The regulatory mechanism of the cells of parathyroid gland proliferation is not exactly known. Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of nuclear receptor superfamily. PPARγ is expressed in adipose tissue at a high level. It plays a role on number of disorders such as adipose tissue differantiation, insulin sensivity, ...

Objective: Tumor induced osteomalacia (TIO) belongs to the group of hypophosphatemic osteomalacias and is induced by a tumor. It is not common disease.Case report: We describe a 34-year-old caucasian man who presented with a 5 year history of diffuse bone pain and muscle weakness. Laboratory investigations showed normal calcium level, low phosphate level between 1.01 mg/dl, and 1.6 mg/dl (reference range: 2.6–5.5 mg/dl), raised alkaline phosphatase ...